1. Renaturation of a completely denatured prion to infectious status has not yet been achieved; however, partially denatured prions can be renatured to an infective status under certain artificial conditions.

2. The substrate and the prions are adiabatically heated to elevated temperatures at which the prions are inactivated.

3. There are three human prion diseases and four main prion diseases of animals.

4. Methods for the detection and treatment of aberrant prion disease

5. Fourthly, acarids full of prions are being found on fodder.

6. Prions are infectious protein molecules that do not contain DNA or RNA.

7. Much prion type diseases can be caused by cannibalism.

8. Even as a Nobel winner, Prusiner must still demonstrate beyond question how prions cause disease.

9. Prion diseases affect the brains of a number of mammals, including humans.

10. The current system for detecting infectious prion particles is not very sensitive.

11. CONCLUSION It is concluded that prion protein has a heterophilic binding.

12. At the forefront of Antisense prion research is a married couple

13. So drugs that prevent this amyloid – prion coupling could be a potent weapon against Alzheimer's.

14. Last week, a Pima County grand jury indicted Prion, charging he killed Vicari.

15. Molecular analysis of prion strain variation and the Aetiology of ‘new variant’ CJD.

16. Method for detection or measurement of abnormal prion protein involved in transmissible spongiform encephalopathy

17. We should transform the traditional medical thinking model to research the mystery of prion.

18. What is even more peculiar : exactly the same prion proteins occur in healthy animals.

19. The malformed prion proteins can be deposited in the brain, thereby destroying brain tissue.

20. MeSH scope note: A transmissible spongiform encephalopathy of cattle associated with abnormal prion proteins in the brain.

21. When he added an anti - prion drug to the mix, though, the virus production halted.

22. List in order of sizes from biggest to smallest: Bacteria, Archea, Protozoa, Fungi, Algae, Virus, Viroid, Prions, Helminths

23. All we have to do is check out parasites, viruses, bacteria, fungi, prions, radiation, toxins, chemicals, or it's internet porn related.

24. However, abnormal prion protein was detected in the recipient’s lymphoid tissues, indicating transmission of infection from an asymptomatic individual.

25. No one has been able to create purified prions in a system that would rule out the presence of viruses.

26. 10 No one has been able to create purified prions in a system that would rule out the presence of viruses.

27. After purification and refoldation of the recombinant OvPrPC, conformational changes of ovine prion protein was triggered by thermal denaturation.

28. While Amyloids can cause devastating economic hardship in an extraordinary variety of settings, we have found that, surprisingly, prions can also be beneficial

29. Healthy proteins, which have not met up with prions, reside quietly in the membranes of nerve cells in the brain.

30. A prion is a type of protein that can trigger normal proteins in the brain to fold Abnormally

31. Prusiner warned that prion proteins could jump from one species to another, a controversial theory now gaining acceptance.

32. There were examples of prion diseases, but the ones that afflicted humans were so rare as to be medical oddities.

33. Antisense treatments are also being investigated for prion disorders, which involve toxic proteins that wreak havoc on the brain

34. Computer models are used to create three-dimensional models of prions, helping scientists understand the structural transformation they undergo to turn deadly.

35. Prusiner, by the way, is the one central character in the prion saga whom Rhodes was unable to interview.

36. Collectively, diseases that are caused by the abnormal folding of the prion protein are known as Transmissible Spongiform Encephalopathies (TSEs).

37. The extraction process permits testing for the presence of abnormal prion protein, e.g., for diagnosis of transmissible spongiform encephalopathies (TSE).

38. Bse (bovine spongiform encephalopathy) is a progressive neurological disorder of cattle that results from infection by an unusual transmissible agent called a prion

39. 29 Accumulating data indicate that heterozygosity at codon 129 plays an important part in the phenotypic expression of familial prion diseases.

40. 'Our results establish the first animal model of a genetic prion disease recapitulating cognitive, motor, and neurophysiological abnormalities of the human disorder,' explained Dr Chiesa.

41. Bse (bovine spongiform encephalopathy) is a progressive neurological disorder of cattle that results from infection by an unusual transmissible agent called a prion

42. "My wife gave me too much pillow talk to persuade me taking briberies, "regretted the former mayor who has been put into prion.

43. Prions are not readily transmittable from species to species, but once they have broken through the species barrier they can rapidly adapt and become contagious within the species.

44. "Because there is no myelin damage at birth, we assumed prions are needed to maintain the quality of the myelin sheath, which diminishes throughout life, " says Aguzzi.

45. The risk of adnexal torsion, ovarian hyperstimulation syndrome (OHSS), thrombosis and embolism, epigenetic alterations, prion transmission via urinary gonadotrophins and cancer are summarized and discussed.

46. Abnormal prion protein deposits with high seeding activities in the skeletal muscle, femoral nerve, and scalp of an Autopsied case of sporadic Creutzfeldt–Jakob disease

47. Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, Bactericides, chemical toxicology and others as examples

48. Pharmaceutical composition for the prevention or treatment of a prion disease containing an active ingredient in the form of the prnp gene using recombinant adenovirus vector

49. Disclosed is a method for the pre-treatment of a sample for detecting or measuring an abnormal prion protein (PrPres) involved in transmissible spongiform encephalopathy (TSE).

50. Transmissible Spongiform Encephalopathies (TSEs) are chronic degenerative nervous diseases characterised by the accumulation of an abnormal isoform of a cellular glycoprotein known as PrP or prion protein).

51. Transmissible Spongiform Encephalopathies (TSEs) are chronic degenerative nervous diseases characterised by the accumulation of an abnormal isoform of a cellular glycoprotein (known as PrP or prion protein).

52. Some subviral particles also cause disease: the transmissible spongiform encephalopathies, which include Kuru, Creutzfeldt–Jakob disease and bovine spongiform encephalopathy ("mad cow disease"), are caused by prions, hepatitis D is due to a satellite virus.

53. BSE is one of a number of transmissible spongiform encephalopathies (TSEs) a characteristic of which is the presence of an abnormal form of a protein called a prion.

54. The present invention relates to a pharmaceutical composition for the prevention or treatment of a prion disease containing an active ingredient in the form of the Prnp gene using a recombinant adenovirus vector.

55. Consequently, The Prnp gene transfection system using a recombinant adenovirus vector according to the present invention protects nerve cells by suppressing PrPSc-mediated nerve cell death, and thus can be used to advantage in the prevention or treatment of prion diseases.

56. Amyloid proteins, mainly including amyloid-β peptides, prion proteins, α-synuclein, copper/zinc superoxide dismutase, as well as the bacterial protein RepA, are characterized by the deposition in a variety of tissues or cells as aggregated species (Amyloids or insoluble deposits or inclusions) that share a distinctive β-sheet-rich fibrillar ultrastructure.

57. Amyloid proteins, mainly including Amyloid-β peptides, prion proteins, α-synuclein, copper/zinc superoxide dismutase, as well as the bacterial protein RepA, are characterized by the deposition in a variety of tissues or cells as aggregated species (Amyloids or insoluble deposits or inclusions) that share a distinctive β-sheet-rich fibrillar ultrastructure.